Good Old New Ways

New ways to keep old promises in health care.

Engineering cardiac muscle: new ways to refurbish old hearts?

Myocardial infarction leads to irreversible cell loss and scar formation, which result in impaired cardiac function, cardiac hypertrophy and, eventually, heart failure. As the intrinsic regenerative capacity of the human heart is very limited, organ transplantation or ventricular assist devices remain the only end-stage therapy options to date. For at least two decades, alternative therapeutic ...

New ways of looking at old issues: inequality and growth

Ž . The paper uses new cross-country data on income and asset land distribution to show Ž . that i there is a strong negative relationship between initial inequality in the asset Ž . distribution and long-term growth; ii inequality reduces income growth for the poor, but Ž . not for the rich; and iii available longitudinal data provide little support for the Kuznets hypothesis. Policies that in...

New Ways to Make Old Walls: Bacterial Surprises

Two papers in this issue of Cell (Paradis-Bleau et al., 2010 and Typas et al., 2010) report that the lipoproteins LpoA and LpoB are required for the synthesis of cell walls in Escherichia coli. Attached to the bacterial outer membrane, these new cell wall components regulate penicillin-binding proteins located at the inner membrane.

Looking both ways: new research on old theories

times of excitement when an unexpected discovery spurs one to more exploration and discovery. One of his such moments was that despite its three macroscopical anatomical divisions and 10 histological, connective tissue-defined segments, the mouse epididymis showed unexpectedly six major clusters of gene activity. The location of gene expression did not correspond to the histological segments, a...